Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases

Complex autoimmune diseases are sexually dimorphic. An interplay between predisposing genetics and sex-related factors probably controls the sex discrepancy in the immune response, but the underlying mechanisms are unclear. Here we positionally identify a polymorphic estrogen receptor binding site t...

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Detalles Bibliográficos
Autores principales: Fernandez Lahore, Gonzalo, Förster, Michael, Johannesson, Martina, Sabatier, Pierre, Lönnblom, Erik, Aoun, Mike, He, Yibo, Nandakumar, Kutty Selva, Zubarev, Roman A., Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458462/
https://www.ncbi.nlm.nih.gov/pubmed/34552089
http://dx.doi.org/10.1038/s41467-021-25828-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458462/
https://www.ncbi.nlm.nih.gov/pubmed/34552089
http://dx.doi.org/10.1038/s41467-021-25828-5

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