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Targeting the actin nucleation promoting factor WASp provides a therapeutic approach for hematopoietic malignancies

Cancer cells depend on actin cytoskeleton rearrangement to carry out hallmark malignant functions including activation, proliferation, migration and invasiveness. Wiskott–Aldrich Syndrome protein (WASp) is an actin nucleation-promoting factor and is a key regulator of actin polymerization in hematop...

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Detalles Bibliográficos
Autores principales:	Biber, Guy, Ben-Shmuel, Aviad, Noy, Elad, Joseph, Noah, Puthenveetil, Abhishek, Reiss, Neria, Levy, Omer, Lazar, Itay, Feiglin, Ariel, Ofran, Yanay, Kedmi, Meirav, Avigdor, Abraham, Fried, Sophia, Barda-Saad, Mira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458504/ https://www.ncbi.nlm.nih.gov/pubmed/34552085 http://dx.doi.org/10.1038/s41467-021-25842-7

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