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5 Year Outcomes of Patients With Aortic Structural Valve Deterioration Treated With Transcatheter Valve in Valve – A Single Center Prospective Registry
The Valve-in-Valve (ViV) technique is an established alternative for the treatment of structural bioprosthetic valve deterioration (SVD). Data describing the intermediate term follow up of patients treated with this approach is scarce. We report on our intermediate-term outcomes of patients with SVD...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458695/ https://www.ncbi.nlm.nih.gov/pubmed/34568456 http://dx.doi.org/10.3389/fcvm.2021.713341 |
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author | Schamroth Pravda, Nili Kornowski, Ran Levi, Amos Witberg, Guy Landes, Uri Perl, Leor Shapira, Yaron Orvin, Katia Mishaev, Raffael Talmor Barkan, Yeela Hamdan, Ashraf Sharoni, Ram Vaknin Assa, Hana Codner, Pablo |
author_facet | Schamroth Pravda, Nili Kornowski, Ran Levi, Amos Witberg, Guy Landes, Uri Perl, Leor Shapira, Yaron Orvin, Katia Mishaev, Raffael Talmor Barkan, Yeela Hamdan, Ashraf Sharoni, Ram Vaknin Assa, Hana Codner, Pablo |
author_sort | Schamroth Pravda, Nili |
collection | PubMed |
description | The Valve-in-Valve (ViV) technique is an established alternative for the treatment of structural bioprosthetic valve deterioration (SVD). Data describing the intermediate term follow up of patients treated with this approach is scarce. We report on our intermediate-term outcomes of patients with SVD in the Aortic position treated with ViV. Included were patients with symptomatic SVD in the aortic position valve who were treated by Valve in valve transcatheter aortic valve implantation (ViV-TAVI) during the years 2010-2019 in our center. Three main outcomes were examined during the follow up period: NYHA functional class, ViV-TAVI hemodynamic per echocardiography, and mortality. Our cohort consisted of 85 patients (mean age 78.8 ± 8.9 years). The indications for aortic ViV were: SVD isolated aortic stenosis in 37.6%, SVD isolated aortic regurgitation in 42.2% and combined valve pathology in 20.0%. Self-expandable and balloon-expandable devices were used in 73 (85.9%) and 12 (14.1%), respectively. Average follow up was 3.7 ± 2.4 years. 95 and 91% of patients were in NYHA functional class I/II at 1 and 5 year follow up respectively. At one year, the mean trans-aortic valve pressure was 15 ± 9 mmHg and rates of ≥ moderate aortic regurgitation were 3.7%. Mortality at one year was 8.6% (95% CI 2.3–14.4) and 31% (95% CI 16.5–42.5) at 5 years. ViV in the aortic position offers an effective and durable treatment option for patient with SVD, with low rates of all-cause mortality, excellent hemodynamic and improved functional capacity at intermediate follow up. |
format | Online Article Text |
id | pubmed-8458695 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84586952021-09-24 5 Year Outcomes of Patients With Aortic Structural Valve Deterioration Treated With Transcatheter Valve in Valve – A Single Center Prospective Registry Schamroth Pravda, Nili Kornowski, Ran Levi, Amos Witberg, Guy Landes, Uri Perl, Leor Shapira, Yaron Orvin, Katia Mishaev, Raffael Talmor Barkan, Yeela Hamdan, Ashraf Sharoni, Ram Vaknin Assa, Hana Codner, Pablo Front Cardiovasc Med Cardiovascular Medicine The Valve-in-Valve (ViV) technique is an established alternative for the treatment of structural bioprosthetic valve deterioration (SVD). Data describing the intermediate term follow up of patients treated with this approach is scarce. We report on our intermediate-term outcomes of patients with SVD in the Aortic position treated with ViV. Included were patients with symptomatic SVD in the aortic position valve who were treated by Valve in valve transcatheter aortic valve implantation (ViV-TAVI) during the years 2010-2019 in our center. Three main outcomes were examined during the follow up period: NYHA functional class, ViV-TAVI hemodynamic per echocardiography, and mortality. Our cohort consisted of 85 patients (mean age 78.8 ± 8.9 years). The indications for aortic ViV were: SVD isolated aortic stenosis in 37.6%, SVD isolated aortic regurgitation in 42.2% and combined valve pathology in 20.0%. Self-expandable and balloon-expandable devices were used in 73 (85.9%) and 12 (14.1%), respectively. Average follow up was 3.7 ± 2.4 years. 95 and 91% of patients were in NYHA functional class I/II at 1 and 5 year follow up respectively. At one year, the mean trans-aortic valve pressure was 15 ± 9 mmHg and rates of ≥ moderate aortic regurgitation were 3.7%. Mortality at one year was 8.6% (95% CI 2.3–14.4) and 31% (95% CI 16.5–42.5) at 5 years. ViV in the aortic position offers an effective and durable treatment option for patient with SVD, with low rates of all-cause mortality, excellent hemodynamic and improved functional capacity at intermediate follow up. Frontiers Media S.A. 2021-09-09 /pmc/articles/PMC8458695/ /pubmed/34568456 http://dx.doi.org/10.3389/fcvm.2021.713341 Text en Copyright © 2021 Schamroth Pravda, Kornowski, Levi, Witberg, Landes, Perl, Shapira, Orvin, Mishaev, Talmor Barkan, Hamdan, Sharoni, Vaknin Assa and Codner. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Schamroth Pravda, Nili Kornowski, Ran Levi, Amos Witberg, Guy Landes, Uri Perl, Leor Shapira, Yaron Orvin, Katia Mishaev, Raffael Talmor Barkan, Yeela Hamdan, Ashraf Sharoni, Ram Vaknin Assa, Hana Codner, Pablo 5 Year Outcomes of Patients With Aortic Structural Valve Deterioration Treated With Transcatheter Valve in Valve – A Single Center Prospective Registry |
title | 5 Year Outcomes of Patients With Aortic Structural Valve Deterioration Treated With Transcatheter Valve in Valve – A Single Center Prospective Registry |
title_full | 5 Year Outcomes of Patients With Aortic Structural Valve Deterioration Treated With Transcatheter Valve in Valve – A Single Center Prospective Registry |
title_fullStr | 5 Year Outcomes of Patients With Aortic Structural Valve Deterioration Treated With Transcatheter Valve in Valve – A Single Center Prospective Registry |
title_full_unstemmed | 5 Year Outcomes of Patients With Aortic Structural Valve Deterioration Treated With Transcatheter Valve in Valve – A Single Center Prospective Registry |
title_short | 5 Year Outcomes of Patients With Aortic Structural Valve Deterioration Treated With Transcatheter Valve in Valve – A Single Center Prospective Registry |
title_sort | 5 year outcomes of patients with aortic structural valve deterioration treated with transcatheter valve in valve – a single center prospective registry |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458695/ https://www.ncbi.nlm.nih.gov/pubmed/34568456 http://dx.doi.org/10.3389/fcvm.2021.713341 |
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