Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review

INTRODUCTION: Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. CASE PRESENTATION: We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metag...

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Detalles Bibliográficos
Autores principales: Luo, Lijuan, Shen, Nan, Chen, Wenjuan, Luo, Chengjuan, Huang, Xiaohang, Jiang, Yuelian, Cao, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458717/
https://www.ncbi.nlm.nih.gov/pubmed/34589678
http://dx.doi.org/10.1002/ped4.12290
Descripción
Sumario:INTRODUCTION: Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. CASE PRESENTATION: We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next‐generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed. CONCLUSION: Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre‐transplant screening and post‐transplant monitoring and prevention in future according to the national conditions of our country.

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