Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review

INTRODUCTION: Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. CASE PRESENTATION: We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metag...

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Autores principales: Luo, Lijuan, Shen, Nan, Chen, Wenjuan, Luo, Chengjuan, Huang, Xiaohang, Jiang, Yuelian, Cao, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458717/
https://www.ncbi.nlm.nih.gov/pubmed/34589678
http://dx.doi.org/10.1002/ped4.12290
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author Luo, Lijuan
Shen, Nan
Chen, Wenjuan
Luo, Chengjuan
Huang, Xiaohang
Jiang, Yuelian
Cao, Qing
author_facet Luo, Lijuan
Shen, Nan
Chen, Wenjuan
Luo, Chengjuan
Huang, Xiaohang
Jiang, Yuelian
Cao, Qing
author_sort Luo, Lijuan
collection PubMed
description INTRODUCTION: Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. CASE PRESENTATION: We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next‐generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed. CONCLUSION: Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre‐transplant screening and post‐transplant monitoring and prevention in future according to the national conditions of our country.
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spelling pubmed-84587172021-09-28 Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review Luo, Lijuan Shen, Nan Chen, Wenjuan Luo, Chengjuan Huang, Xiaohang Jiang, Yuelian Cao, Qing Pediatr Investig Case Report INTRODUCTION: Toxoplasmosis is a life‐threatening complication after hematopoietic stem cell transplantation (HSCT). However, for several reasons, clinicians know little about Toxoplasma infection. CASE PRESENTATION: We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next‐generation sequencing (mNGS) after HSCT in a boy. Additionally, we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed. CONCLUSION: Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre‐transplant screening and post‐transplant monitoring and prevention in future according to the national conditions of our country. John Wiley and Sons Inc. 2021-09-22 /pmc/articles/PMC8458717/ /pubmed/34589678 http://dx.doi.org/10.1002/ped4.12290 Text en © 2021 Chinese Medical Association. Pediatric Investigation published by John Wiley & Sons Australia, Ltd on behalf of Futang Research Center of Pediatric Development. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Luo, Lijuan
Shen, Nan
Chen, Wenjuan
Luo, Chengjuan
Huang, Xiaohang
Jiang, Yuelian
Cao, Qing
Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review
title Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review
title_full Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review
title_fullStr Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review
title_full_unstemmed Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review
title_short Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review
title_sort toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458717/
https://www.ncbi.nlm.nih.gov/pubmed/34589678
http://dx.doi.org/10.1002/ped4.12290
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