Cargando…
β-caryophyllene, an FDA-Approved Food Additive, Inhibits Methamphetamine-Taking and Methamphetamine-Seeking Behaviors Possibly via CB2 and Non-CB2 Receptor Mechanisms
Recent research indicates that brain cannabinoid CB2 receptors are involved in drug reward and addiction. However, it is unclear whether β-caryophyllene (BCP), a natural product with a CB2 receptor agonist profile, has therapeutic effects on methamphetamine (METH) abuse and dependence. In this study...
Autores principales: | He, Xiang-Hu, Galaj, Ewa, Bi, Guo-Hua, He, Yi, Hempel, Briana, Wang, Yan-Lin, Gardner, Eliot L., Xi, Zheng-Xiong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458938/ https://www.ncbi.nlm.nih.gov/pubmed/34566647 http://dx.doi.org/10.3389/fphar.2021.722476 |
Ejemplares similares
-
Therapeutic potential of PIMSR, a novel CB1 receptor neutral antagonist, for cocaine use disorder: evidence from preclinical research
por: Galaj, Ewa, et al.
Publicado: (2022) -
Footshock-Induced Abstinence from Compulsive Methamphetamine Self-administration in Rat Model Is Accompanied by Increased Hippocampal Expression of Cannabinoid Receptors (CB1 and CB2)
por: Jayanthi, Subramaniam, et al.
Publicado: (2022) -
β-Caryophyllene Reduces the Inflammatory Phenotype of Periodontal Cells by Targeting CB2 Receptors
por: Picciolo, Giacomo, et al.
Publicado: (2020) -
Methamphetamine Blocks Adenosine A(2A) Receptor Activation via Sigma 1 and Cannabinoid CB(1) Receptors
por: Casanovas, Mireia, et al.
Publicado: (2021) -
Coupling of CB-2 and CB-1
por: Ansaldo
Publicado: (2003)