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PIEZO1 Ion Channel Mediates Ionizing Radiation-Induced Pulmonary Endothelial Cell Ferroptosis via Ca(2+)/Calpain/VE-Cadherin Signaling

Pulmonary endothelial cell dysfunction plays an important role in ionizing radiation (IR)-induced lung injury. Whether pulmonary endothelial cell ferroptosis occurs after IR and what are the underlying mechanisms remain elusive. Here, we demonstrate that 15-Gy IR induced ferroptosis characterized by...

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Detalles Bibliográficos
Autores principales:	Guo, Xue-Wei, Zhang, Hao, Huang, Jia-Qi, Wang, Si-Nian, Lu, Yan, Cheng, Bo, Dong, Su-He, Wang, Ying-Ying, Li, Feng-Sheng, Li, Yong-Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458942/ https://www.ncbi.nlm.nih.gov/pubmed/34568428 http://dx.doi.org/10.3389/fmolb.2021.725274

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