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Risk Factors and Prevention of Viral Hepatitis-Related Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a common cancer in the world, and its incidence is increasing yearly. Hepatitis B virus (HBV) infection and hepatitis C virus (HCV) infection are important causes of HCC. Liver cirrhosis, age, sex, smoking and drinking, and metabolic risk factors will increase the r...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458967/ https://www.ncbi.nlm.nih.gov/pubmed/34568017 http://dx.doi.org/10.3389/fonc.2021.686962 |
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author | Zhang, Xinhe Guan, Lin Tian, Haoyu Zeng, Zilu Chen, Jiayu Huang, Die Sun, Ji Guo, Jiaqi Cui, Huipeng Li, Yiling |
author_facet | Zhang, Xinhe Guan, Lin Tian, Haoyu Zeng, Zilu Chen, Jiayu Huang, Die Sun, Ji Guo, Jiaqi Cui, Huipeng Li, Yiling |
author_sort | Zhang, Xinhe |
collection | PubMed |
description | Hepatocellular carcinoma (HCC) is a common cancer in the world, and its incidence is increasing yearly. Hepatitis B virus (HBV) infection and hepatitis C virus (HCV) infection are important causes of HCC. Liver cirrhosis, age, sex, smoking and drinking, and metabolic risk factors will increase the risk of cancer in HBV/HCV patients. And viral load, APRI, FIB-4, and liver stiffness can all predict the risk of HCC in patients with viral infection. In addition, effective prevention strategies are essential in reducing the risk of HCC. The prevention of HCC involves mainly tertiary prevention strategies, while the primary prevention is based on standardized vaccine injections to prevent the occurrence of HBV/HCV. Eliminating the route of transmission and vaccination will lead to a decrease in the incidence of HCC. Secondary prevention involves effective antiviral treatment of HBV/HCV to prevent the disease from progressing to HCC, and tertiary prevention is actively treating HCC to prevent its recurrence. |
format | Online Article Text |
id | pubmed-8458967 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84589672021-09-24 Risk Factors and Prevention of Viral Hepatitis-Related Hepatocellular Carcinoma Zhang, Xinhe Guan, Lin Tian, Haoyu Zeng, Zilu Chen, Jiayu Huang, Die Sun, Ji Guo, Jiaqi Cui, Huipeng Li, Yiling Front Oncol Oncology Hepatocellular carcinoma (HCC) is a common cancer in the world, and its incidence is increasing yearly. Hepatitis B virus (HBV) infection and hepatitis C virus (HCV) infection are important causes of HCC. Liver cirrhosis, age, sex, smoking and drinking, and metabolic risk factors will increase the risk of cancer in HBV/HCV patients. And viral load, APRI, FIB-4, and liver stiffness can all predict the risk of HCC in patients with viral infection. In addition, effective prevention strategies are essential in reducing the risk of HCC. The prevention of HCC involves mainly tertiary prevention strategies, while the primary prevention is based on standardized vaccine injections to prevent the occurrence of HBV/HCV. Eliminating the route of transmission and vaccination will lead to a decrease in the incidence of HCC. Secondary prevention involves effective antiviral treatment of HBV/HCV to prevent the disease from progressing to HCC, and tertiary prevention is actively treating HCC to prevent its recurrence. Frontiers Media S.A. 2021-09-09 /pmc/articles/PMC8458967/ /pubmed/34568017 http://dx.doi.org/10.3389/fonc.2021.686962 Text en Copyright © 2021 Zhang, Guan, Tian, Zeng, Chen, Huang, Sun, Guo, Cui and Li https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Zhang, Xinhe Guan, Lin Tian, Haoyu Zeng, Zilu Chen, Jiayu Huang, Die Sun, Ji Guo, Jiaqi Cui, Huipeng Li, Yiling Risk Factors and Prevention of Viral Hepatitis-Related Hepatocellular Carcinoma |
title | Risk Factors and Prevention of Viral Hepatitis-Related Hepatocellular Carcinoma |
title_full | Risk Factors and Prevention of Viral Hepatitis-Related Hepatocellular Carcinoma |
title_fullStr | Risk Factors and Prevention of Viral Hepatitis-Related Hepatocellular Carcinoma |
title_full_unstemmed | Risk Factors and Prevention of Viral Hepatitis-Related Hepatocellular Carcinoma |
title_short | Risk Factors and Prevention of Viral Hepatitis-Related Hepatocellular Carcinoma |
title_sort | risk factors and prevention of viral hepatitis-related hepatocellular carcinoma |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458967/ https://www.ncbi.nlm.nih.gov/pubmed/34568017 http://dx.doi.org/10.3389/fonc.2021.686962 |
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