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A single copy transgenic mutant FUS strain reproduces age-dependent ALS phenotypes in C. elegans

Mutations in the human DNA/RNA binding protein FUS are associated with amyotrophic lateral sclerosis and frontotemporal lobar degeneration, including some aggressive and juvenile onset forms. Cytoplasmic inclusions of human FUS proteins are observed in various neurodegenerative disorders, such as Hu...

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Detalles Bibliográficos
Autores principales:	Labarre, Audrey, Tossing, Gilles, Maios, Claudia, Doyle, James J, Parker, J Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Caltech Library 2021
Materias:	New Finding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459179/ https://www.ncbi.nlm.nih.gov/pubmed/34568776 http://dx.doi.org/10.17912/micropub.biology.000473

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