Identification of molecular glues of the SLP76/14-3-3 protein–protein interaction

The stabilisation of protein–protein interactions (PPIs) through molecular glues is a novel and promising approach in drug discovery. In stark contrast to research in protein–protein inhibition the field of stabilisation remains underdeveloped with comparatively few examples of small-molecule stabil...

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Detalles Bibliográficos
Autores principales: Soini, Lorenzo, Redhead, Martin, Westwood, Marta, Leysen, Seppe, Davis, Jeremy, Ottmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459327/
https://www.ncbi.nlm.nih.gov/pubmed/34667951
http://dx.doi.org/10.1039/d1md00172h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459327/
https://www.ncbi.nlm.nih.gov/pubmed/34667951
http://dx.doi.org/10.1039/d1md00172h

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