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Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract

[Image: see text] A AuNP-modified screen-printed carbon electrode (AuNP/SPCE) for monitoring important biomolecules, such as dopamine (DA) and riboflavin (RF), having a high potential for personalized medicine and for continuous monitoring of human health is here proposed. AuNPs were synthesized usi...

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Autores principales: Chelly, Sabrine, Chelly, Meryam, Zribi, Rayhane, Gdoura, Radhouane, Bouaziz-Ketata, Hanen, Neri, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459371/
https://www.ncbi.nlm.nih.gov/pubmed/34568646
http://dx.doi.org/10.1021/acsomega.1c00793
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author Chelly, Sabrine
Chelly, Meryam
Zribi, Rayhane
Gdoura, Radhouane
Bouaziz-Ketata, Hanen
Neri, Giovanni
author_facet Chelly, Sabrine
Chelly, Meryam
Zribi, Rayhane
Gdoura, Radhouane
Bouaziz-Ketata, Hanen
Neri, Giovanni
author_sort Chelly, Sabrine
collection PubMed
description [Image: see text] A AuNP-modified screen-printed carbon electrode (AuNP/SPCE) for monitoring important biomolecules, such as dopamine (DA) and riboflavin (RF), having a high potential for personalized medicine and for continuous monitoring of human health is here proposed. AuNPs were synthesized using the extract of Rhanterium suaveolens as a reducing medium and were characterized by UV–vis spectroscopy, dynamic light scattering (DLS), and scanning and transmission electron microscopy (SEM and TEM). The synthesized AuNPs appear spherical and present a bimodal size distribution with a maximum centered at around 30–50 nm. Cyclic voltammetry (CV) experiments demonstrated that the modified AuNP/SPCE sensor exhibits superior electrochemical performances to the bare SPCE. Low limits of detection (LODs) of 0.2 and 0.07 μM at S/N = 3 and sensitivities of 550.4  and 2399 μA mM(–1) cm(–2) were registered for DA and RF detection, respectively. Results demonstrate the promising electrochemical characteristics of the synthesized AuNPs and developed AuNP/SPCE electrochemical sensor for the determination of these important biomolecules.
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spelling pubmed-84593712021-09-24 Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract Chelly, Sabrine Chelly, Meryam Zribi, Rayhane Gdoura, Radhouane Bouaziz-Ketata, Hanen Neri, Giovanni ACS Omega [Image: see text] A AuNP-modified screen-printed carbon electrode (AuNP/SPCE) for monitoring important biomolecules, such as dopamine (DA) and riboflavin (RF), having a high potential for personalized medicine and for continuous monitoring of human health is here proposed. AuNPs were synthesized using the extract of Rhanterium suaveolens as a reducing medium and were characterized by UV–vis spectroscopy, dynamic light scattering (DLS), and scanning and transmission electron microscopy (SEM and TEM). The synthesized AuNPs appear spherical and present a bimodal size distribution with a maximum centered at around 30–50 nm. Cyclic voltammetry (CV) experiments demonstrated that the modified AuNP/SPCE sensor exhibits superior electrochemical performances to the bare SPCE. Low limits of detection (LODs) of 0.2 and 0.07 μM at S/N = 3 and sensitivities of 550.4  and 2399 μA mM(–1) cm(–2) were registered for DA and RF detection, respectively. Results demonstrate the promising electrochemical characteristics of the synthesized AuNPs and developed AuNP/SPCE electrochemical sensor for the determination of these important biomolecules. American Chemical Society 2021-09-09 /pmc/articles/PMC8459371/ /pubmed/34568646 http://dx.doi.org/10.1021/acsomega.1c00793 Text en © 2021 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Chelly, Sabrine
Chelly, Meryam
Zribi, Rayhane
Gdoura, Radhouane
Bouaziz-Ketata, Hanen
Neri, Giovanni
Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract
title Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract
title_full Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract
title_fullStr Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract
title_full_unstemmed Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract
title_short Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract
title_sort electrochemical detection of dopamine and riboflavine on a screen-printed carbon electrode modified by aunps derived from rhanterium suaveolens plant extract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459371/
https://www.ncbi.nlm.nih.gov/pubmed/34568646
http://dx.doi.org/10.1021/acsomega.1c00793
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