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Design, Synthesis, and the Effects of (E)-9-Oxooctadec-10-en-12-ynoic Acid Analogues to Promote Glucose Uptake

[Image: see text] (E)-9-Oxooctadec-10-en-12-ynoic acid is found to mediate its antidiabetic activity by increasing insulin-stimulated glucose uptake in L6 myotubes by activating the phosphoinositide 3-kinase (PI3K) pathway. A simultaneous study of site-specific modification followed by structure–act...

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Detalles Bibliográficos
Autores principales:	Kshirsagar, Rajendra R., Gadekar, Pradip K., Khedkar, Vijay M., Vijayakumar, Vijayaparthasarathi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459440/ https://www.ncbi.nlm.nih.gov/pubmed/34568690 http://dx.doi.org/10.1021/acsomega.1c03600

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