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LDLR gene polymorphism (rs688) affects susceptibility to cardiovascular disease in end-stage kidney disease patients

BACKGROUND: The low-density lipoprotein receptor (LDLR) plays a significant role in maintaining the cellular cholesterol homeostasis. Mutations in the LDLR gene can lead to a significant rise in plasma LDL levels that may result in an increased risk of atherosclerosis and coronary heart disease. The...

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Detalles Bibliográficos
Autores principales: Buraczynska, Monika, Jacob, Jerry, Gwiazda-Tyndel, Karolina, Ksiazek, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459523/
https://www.ncbi.nlm.nih.gov/pubmed/34556050
http://dx.doi.org/10.1186/s12882-021-02532-6