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LDLR gene polymorphism (rs688) affects susceptibility to cardiovascular disease in end-stage kidney disease patients
BACKGROUND: The low-density lipoprotein receptor (LDLR) plays a significant role in maintaining the cellular cholesterol homeostasis. Mutations in the LDLR gene can lead to a significant rise in plasma LDL levels that may result in an increased risk of atherosclerosis and coronary heart disease. The...
Autores principales: | Buraczynska, Monika, Jacob, Jerry, Gwiazda-Tyndel, Karolina, Ksiazek, Andrzej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459523/ https://www.ncbi.nlm.nih.gov/pubmed/34556050 http://dx.doi.org/10.1186/s12882-021-02532-6 |
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