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E3 ligase activity of Carboxyl terminus of Hsc70 interacting protein (CHIP) in Wharton's jelly derived mesenchymal stem cells improves their persistence under hyperglycemic stress and promotes the prophylactic effects against diabetic cardiac damages

Recent studies indicate that umbilical cord stem cells are cytoprotective against several disorders. One critical limitation in using stem cells is reduction in their viability under stressful conditions, such as diabetes. However, the molecular intricacies responsible for diabetic conditions are no...

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Detalles Bibliográficos
Autores principales: Ali, Ayaz, Kuo, Wei‐Wen, Kuo, Chia‐Hua, Lo, Jeng‐Fan, Chen, Michael Y. C., Daddam, Jayasimha R., Ho, Tsung‐Jung, Viswanadha, Vijaya Padma, Shibu, Marthandam Asokan, Huang, Chih‐Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459600/
https://www.ncbi.nlm.nih.gov/pubmed/34589606
http://dx.doi.org/10.1002/btm2.10234