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HLA-G1(+) Expression in GGTA1KO Pigs Suppresses Human and Monkey Anti-Pig T, B and NK Cell Responses

The human leukocyte antigen G1 (HLA-G1), a non-classical class I major histocompatibility complex (MHC-I) protein, is a potent immunomodulatory molecule at the maternal/fetal interface and other environments to regulate the cellular immune response. We created GGTA1(-)/HLAG1(+) pigs to explore their...

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Detalles Bibliográficos
Autores principales:	Rao, Joseph Sushil, Hosny, Nora, Kumbha, Ramesh, Naqvi, Raza Ali, Singh, Amar, Swanson, Zachary, Levy, Heather, Matson, Anders W., Steinhoff, Magie, Forneris, Nicole, Walters, Eric, Hering, Bernhard J., Burlak, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459615/ https://www.ncbi.nlm.nih.gov/pubmed/34566993 http://dx.doi.org/10.3389/fimmu.2021.730545

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