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Engineering an Antibody V Gene-Selective Vaccine
The ligand-binding surface of the B cell receptor (BCR) is formed by encoded and non-encoded antigen complementarity determining regions (CDRs). Genetically reproducible or ‘public’ antibodies can arise when the encoded CDRs play deterministic roles in antigen recognition, notably within human broad...
Autores principales: | Ronsard, Larance, Yousif, Ashraf S., Peabody, Julianne, Okonkwo, Vintus, Devant, Pascal, Mogus, Alemu Tekewe, Barnes, Ralston M., Rohrer, Daniel, Lonberg, Nils, Peabody, David, Chackerian, Bryce, Lingwood, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459710/ https://www.ncbi.nlm.nih.gov/pubmed/34566992 http://dx.doi.org/10.3389/fimmu.2021.730471 |
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