Duplex formation between the template and the nascent strand in the transcription-regulating sequences is associated with the site of template switching in SARS – CoV-2

Recently published transcriptomic data of the SARS-CoV-2 coronavirus show that there is a large variation in the frequency and steady state levels of subgenomic mRNA sequences. This variation is derived from discontinuous subgenomic RNA synthesis, where the polymerase switches template from a 3ʹ pro...

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Detalles Bibliográficos
Autores principales: D’Souza, Aaron R., Buckingham, Amanda B., Salasc, Fanny, Ingemarsdotter, Carin K., Iaconis, Gennaro, Jarvis, Isobel, Groom, Harriet C. T., Kenyon, Julia C., Lever, Andrew M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8459930/
https://www.ncbi.nlm.nih.gov/pubmed/34541994
http://dx.doi.org/10.1080/15476286.2021.1975388

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