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Rare variants in the endocytic pathway are associated with Alzheimer’s disease, its related phenotypes, and functional consequences

Late-onset Alzheimer’s disease (LOAD) is the most common type of dementia causing irreversible brain damage to the elderly and presents a major public health challenge. Clinical research and genome-wide association studies have suggested a potential contribution of the endocytic pathway to AD, with...

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Detalles Bibliográficos
Autores principales: Zhan, Lingyu, Li, Jiajin, Jew, Brandon, Sul, Jae Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460036/
https://www.ncbi.nlm.nih.gov/pubmed/34516545
http://dx.doi.org/10.1371/journal.pgen.1009772