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Rare variants in the endocytic pathway are associated with Alzheimer’s disease, its related phenotypes, and functional consequences
Late-onset Alzheimer’s disease (LOAD) is the most common type of dementia causing irreversible brain damage to the elderly and presents a major public health challenge. Clinical research and genome-wide association studies have suggested a potential contribution of the endocytic pathway to AD, with...
Autores principales: | Zhan, Lingyu, Li, Jiajin, Jew, Brandon, Sul, Jae Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460036/ https://www.ncbi.nlm.nih.gov/pubmed/34516545 http://dx.doi.org/10.1371/journal.pgen.1009772 |
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