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Ropivacaine-Loaded Poloxamer Binary Hydrogels for Prolonged Regional Anesthesia: Structural Aspects, Biocompatibility, and Pharmacological Evaluation

This study reports the development of thermosensitive hydrogels for delivering ropivacaine (RVC), a wide clinically used local anesthetic. For this purpose, poloxamer- (PL-) based hydrogels were synthesized for evaluating the influence of polymer concentration, hydrophilic-lipophilic balances, and b...

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Detalles Bibliográficos
Autores principales:	Mariano, Kelli Cristina Freitas, Papini, Juliana Zampoli Boava, de Faria, Naially Cardoso, Heluany, Daniele Nicoli Cabral, Botega, Ana Luiza Lourençoni, Cereda, Cíntia Maria Saia, de Paula, Eneida, Tófoli, Giovana Radomille, de Araujo, Daniele Ribeiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460376/ https://www.ncbi.nlm.nih.gov/pubmed/34568494 http://dx.doi.org/10.1155/2021/7300098

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