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Longevity leap: mind the healthspan gap
Life expectancy has increased by three decades since the mid-twentieth century. Parallel healthspan expansion has however not followed, largely impeded by the pandemic of chronic diseases afflicting a growing older population. The lag in quality of life is a recognized challenge that calls for prior...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460831/ https://www.ncbi.nlm.nih.gov/pubmed/34556664 http://dx.doi.org/10.1038/s41536-021-00169-5 |
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author | Garmany, Armin Yamada, Satsuki Terzic, Andre |
author_facet | Garmany, Armin Yamada, Satsuki Terzic, Andre |
author_sort | Garmany, Armin |
collection | PubMed |
description | Life expectancy has increased by three decades since the mid-twentieth century. Parallel healthspan expansion has however not followed, largely impeded by the pandemic of chronic diseases afflicting a growing older population. The lag in quality of life is a recognized challenge that calls for prioritization of disease-free longevity. Contemporary communal, clinical and research trends aspiring to extend the health horizon are here outlined in the context of an evolving epidemiology. A shared action integrating public and societal endeavors with emerging interventions that target age-related multimorbidity and frailty is needed. A multidimensional buildout of a curative perspective, boosted by modern anti-senescent and regenerative technology with augmented decision making, would require dedicated resources and cost-effective validation to responsibly bridge the healthspan-lifespan gap for a future of equitable global wellbeing. |
format | Online Article Text |
id | pubmed-8460831 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84608312021-10-08 Longevity leap: mind the healthspan gap Garmany, Armin Yamada, Satsuki Terzic, Andre NPJ Regen Med Perspective Life expectancy has increased by three decades since the mid-twentieth century. Parallel healthspan expansion has however not followed, largely impeded by the pandemic of chronic diseases afflicting a growing older population. The lag in quality of life is a recognized challenge that calls for prioritization of disease-free longevity. Contemporary communal, clinical and research trends aspiring to extend the health horizon are here outlined in the context of an evolving epidemiology. A shared action integrating public and societal endeavors with emerging interventions that target age-related multimorbidity and frailty is needed. A multidimensional buildout of a curative perspective, boosted by modern anti-senescent and regenerative technology with augmented decision making, would require dedicated resources and cost-effective validation to responsibly bridge the healthspan-lifespan gap for a future of equitable global wellbeing. Nature Publishing Group UK 2021-09-23 /pmc/articles/PMC8460831/ /pubmed/34556664 http://dx.doi.org/10.1038/s41536-021-00169-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Perspective Garmany, Armin Yamada, Satsuki Terzic, Andre Longevity leap: mind the healthspan gap |
title | Longevity leap: mind the healthspan gap |
title_full | Longevity leap: mind the healthspan gap |
title_fullStr | Longevity leap: mind the healthspan gap |
title_full_unstemmed | Longevity leap: mind the healthspan gap |
title_short | Longevity leap: mind the healthspan gap |
title_sort | longevity leap: mind the healthspan gap |
topic | Perspective |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460831/ https://www.ncbi.nlm.nih.gov/pubmed/34556664 http://dx.doi.org/10.1038/s41536-021-00169-5 |
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