Medical Case Report on Repeat Treatment of Restless Legs Syndrome with Intravenous Infusion of Iron

Restless legs syndrome (RLS) is a debilitating neurological disorder for which a range of medical interventions with varied efficacy has been employed. Based on evidence of iron deficiency in the substantia nigra of the midbrain, there are reports of substantial benefits from intravenous iron infusi...

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Autores principales: Condon, Katherine, Chipman, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Single Case − General Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460929/
https://www.ncbi.nlm.nih.gov/pubmed/34703445
http://dx.doi.org/10.1159/000518911
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author Condon, Katherine
Chipman, James
author_facet Condon, Katherine
Chipman, James
author_sort Condon, Katherine
collection PubMed
description Restless legs syndrome (RLS) is a debilitating neurological disorder for which a range of medical interventions with varied efficacy has been employed. Based on evidence of iron deficiency in the substantia nigra of the midbrain, there are reports of substantial benefits from intravenous iron infusion. This case report demonstrates a strong statistically significant negative correlation between serum ferritin and RLS severity of symptoms in a subject with RLS who received 2 intravenous infusions of ferric carboxymaltose over a period of 464 days. The results provide further evidence to support the treatment strategy.
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spelling pubmed-84609292021-10-25 Medical Case Report on Repeat Treatment of Restless Legs Syndrome with Intravenous Infusion of Iron Condon, Katherine Chipman, James Case Rep Neurol Single Case − General Neurology Restless legs syndrome (RLS) is a debilitating neurological disorder for which a range of medical interventions with varied efficacy has been employed. Based on evidence of iron deficiency in the substantia nigra of the midbrain, there are reports of substantial benefits from intravenous iron infusion. This case report demonstrates a strong statistically significant negative correlation between serum ferritin and RLS severity of symptoms in a subject with RLS who received 2 intravenous infusions of ferric carboxymaltose over a period of 464 days. The results provide further evidence to support the treatment strategy. S. Karger AG 2021-09-02 /pmc/articles/PMC8460929/ /pubmed/34703445 http://dx.doi.org/10.1159/000518911 Text en Copyright © 2021 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case − General Neurology
Condon, Katherine
Chipman, James
Medical Case Report on Repeat Treatment of Restless Legs Syndrome with Intravenous Infusion of Iron
title Medical Case Report on Repeat Treatment of Restless Legs Syndrome with Intravenous Infusion of Iron
title_full Medical Case Report on Repeat Treatment of Restless Legs Syndrome with Intravenous Infusion of Iron
title_fullStr Medical Case Report on Repeat Treatment of Restless Legs Syndrome with Intravenous Infusion of Iron
title_full_unstemmed Medical Case Report on Repeat Treatment of Restless Legs Syndrome with Intravenous Infusion of Iron
title_short Medical Case Report on Repeat Treatment of Restless Legs Syndrome with Intravenous Infusion of Iron
title_sort medical case report on repeat treatment of restless legs syndrome with intravenous infusion of iron
topic Single Case − General Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8460929/
https://www.ncbi.nlm.nih.gov/pubmed/34703445
http://dx.doi.org/10.1159/000518911
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