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The oxidation‐resistant CaMKII‐MM281/282VV mutation does not prevent arrhythmias in CPVT1

Catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1) is an inherited arrhythmogenic disorder caused by missense mutations in the cardiac ryanodine receptors (RyR2), that result in increased β‐adrenoceptor stimulation‐induced diastolic Ca(2+) leak. We have previously shown that exerci...

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Detalles Bibliográficos
Autores principales: Sadredini, Mani, Manotheepan, Ravinea, Lehnart, Stephan E., Anderson, Mark E., Sjaastad, Ivar, Stokke, Mathis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461029/
https://www.ncbi.nlm.nih.gov/pubmed/34558218
http://dx.doi.org/10.14814/phy2.15030

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