Cargando…

Inhibition of BCL9 Modulates the Cellular Landscape of Tumor-Associated Macrophages in the Tumor Immune Microenvironment of Colorectal Cancer

Tumor-associated macrophages (TAMs) are an indispensable part of the tumor microenvironment (TME), and they likely play a negative rather than positive role in cancer treatment. However, the cellular landscape and transcriptional profile regulation of TAMs in the case of tumor gene inactivation or c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Zhuang, Yang, Mengxuan, Feng, Mei, Wu, Zhongen, Rosin-Arbesfeld, Rina, Dong, Jibin, Zhu, Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461101/ https://www.ncbi.nlm.nih.gov/pubmed/34566638 http://dx.doi.org/10.3389/fphar.2021.713331

Ejemplares similares

Bcl9 Depletion Modulates Endothelial Cell in Tumor Immune Microenvironment in Colorectal Cancer Tumor
por: Wei, Zhuang, et al.
Publicado: (2021)

Pharmacological Inhibition and Genetic Knockdown of BCL9 Modulate the Cellular Landscape of Cancer-Associated Fibroblasts in the Tumor-Immune Microenvironment of Colorectal Cancer
por: Yang, Mengxuan, et al.
Publicado: (2021)

Identification of angiogenesis-related subtypes, the development of prognostic models, and the landscape of tumor microenvironment infiltration in colorectal cancer
por: Zhang, Chen, et al.
Publicado: (2023)

Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy
por: Li, Weizhen, et al.
Publicado: (2021)

Roles and new Insights of Macrophages in the Tumor Microenvironment of Thyroid Cancer
por: Liu, Qi, et al.
Publicado: (2022)

Detection of a Tumor Suppressor Gene Variant Predisposing to Colorectal Cancer in an 18th Century Hungarian Mummy
por: Feldman, Michal, et al.
Publicado: (2016)

Galloflavin Relieves the Malignant Behavior of Colorectal Cancer Cells in the Inflammatory Tumor Microenvironment
por: Guo, Li, et al.
Publicado: (2021)

Role of microbes in colorectal cancer therapy: Cross-talk between the microbiome and tumor microenvironment
por: Xia, Cong, et al.
Publicado: (2022)

Tumor Microenvironment Targeted Nanotherapy
por: Fernandes, Clara, et al.
Publicado: (2018)

Modulating the Tumor Microenvironment to Enhance Tumor Nanomedicine Delivery
por: Zhang, Bo, et al.
Publicado: (2017)

The significance of glycolysis in tumor progression and its relationship with the tumor microenvironment
por: Zhou, Daoying, et al.
Publicado: (2022)

An intravenous anesthetic drug-propofol, influences the biological characteristics of malignant tumors and reshapes the tumor microenvironment: A narrative literature review
por: Zhou, Xueliang, et al.
Publicado: (2022)

The Role of Tumor Inflammatory Microenvironment in Lung Cancer
por: Tan, Zhaofeng, et al.
Publicado: (2021)

Evidence That Tumor Microenvironment Initiates Epithelial-To-Mesenchymal Transition and Calebin A can Suppress it in Colorectal Cancer Cells
por: Buhrmann, Constanze, et al.
Publicado: (2021)

Co-Targeting Tumor Angiogenesis and Immunosuppressive Tumor Microenvironment: A Perspective in Ethnopharmacology
por: Zhou, Jianbo, et al.
Publicado: (2022)

Mechanisms of tumor-associated macrophages affecting the progression of hepatocellular carcinoma
por: Yuan, Yi, et al.
Publicado: (2023)

Effects of Glycolysis-Related Genes on Prognosis and the Tumor Microenvironment of Hepatocellular Carcinoma
por: Zheng, Ju-Yan, et al.
Publicado: (2022)

Immune Landscape of Colorectal Cancer Tumor Microenvironment from Different Primary Tumor Location
por: Zhang, Longhui, et al.
Publicado: (2018)

SLC11A1 associated with tumor microenvironment is a potential biomarker of prognosis and immunotherapy efficacy for colorectal cancer
por: Ma, Yiming, et al.
Publicado: (2022)

BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer
por: Feng, Mei, et al.
Publicado: (2021)

New and Paradoxical Roles of Matrix Metalloproteinases in the Tumor Microenvironment
por: Noël, Agnès, et al.
Publicado: (2012)

Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment
por: Leroi, Natacha, et al.
Publicado: (2016)

Combinatorial regimens of chemotherapeutic agents: A new perspective on raising the heat of the tumor immune microenvironment
por: Liu, Jingyang, et al.
Publicado: (2022)

Wnt signaling pathway-derived score for predicting therapeutic resistance and tumor microenvironment in lung adenocarcinoma
por: Zhou, Hao-min, et al.
Publicado: (2023)

The role of peroxisome proliferator-activated receptors in the tumor microenvironment, tumor cell metabolism, and anticancer therapy
por: Sun, Jiaao, et al.
Publicado: (2023)

Gut macrophage phenotype is dependent on the tumor microenvironment in colorectal cancer
por: Norton, Samuel E, et al.
Publicado: (2016)

Macrophages in Tumor Microenvironments and the Progression of Tumors
por: Hao, Ning-Bo, et al.
Publicado: (2012)

The Evasion Mechanisms of Cancer Immunity and Drug Intervention in the Tumor Microenvironment
por: Kim, Seong Keun, et al.
Publicado: (2022)

Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment
por: Pan, Cheng, et al.
Publicado: (2020)

Visualizing movement in the tumor microenvironment landscape
por: Calvo, Veronica, et al.
Publicado: (2013)

Targeting Accessories to the Crime: Nanoparticle Nucleic Acid Delivery to the Tumor Microenvironment
por: Harrison, Emily B., et al.
Publicado: (2018)

Tumor Microenvironment–Responsive Polypeptide Nanogels for Controlled Antitumor Drug Delivery
por: Liu, Yanhong, et al.
Publicado: (2021)

Link of sorafenib resistance with the tumor microenvironment in hepatocellular carcinoma: Mechanistic insights
por: Tian, Xinchen, et al.
Publicado: (2022)

Environmental exposure and the role of AhR in the tumor microenvironment of breast cancer
por: Sweeney, Colleen, et al.
Publicado: (2022)

Resistance mechanisms of immune checkpoint inhibition in lymphoma: Focusing on the tumor microenvironment
por: Zhang, Chunlan, et al.
Publicado: (2023)

Editorial: Anti-cancer effects of botanical drugs targeting the tumor microenvironment
por: Cheng, Chien-shan, et al.
Publicado: (2023)

Tumor-Associated Macrophages: Protumoral Macrophages in Inflammatory Tumor Microenvironment
por: Malekghasemi, Somaiyeh, et al.
Publicado: (2020)

Editorial: Crosstalk between cancer-associated fibroblasts and tumor cells in the tumor microenvironment: an emerging target of anti-cancer immunotherapy
por: Zhang, Chunxue, et al.
Publicado: (2023)

Bacteria and macrophages in the tumor microenvironment
por: Xu, Shiyao, et al.
Publicado: (2023)

Macrophages in the Glioblastoma Tumor Microenvironment
por: Coniglio, Salvatore J.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0918dumo4v27319bpsm20890n7