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S100B Inhibition Attenuates Intestinal Damage and Diarrhea Severity During Clostridioides difficile Infection by Modulating Inflammatory Response

The involvement of the enteric nervous system, which is a source of S100B, in Clostridioides difficile (C. difficile) infection (CDI) is poorly understood although intestinal motility dysfunctions are known to occur following infection. Here, we investigated the role of S100B in CDI and examined the...

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Detalles Bibliográficos
Autores principales: Costa, Deiziane V. S., Moura-Neto, Vivaldo, Bolick, David T., Guerrant, Richard L., Fawad, Jibraan A., Shin, Jae H., Medeiros, Pedro H. Q. S., Ledwaba, Solanka E., Kolling, Glynis L., Martins, Conceição S., Venkataraman, Venkat, Warren, Cirle A., Brito, Gerly A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461106/
https://www.ncbi.nlm.nih.gov/pubmed/34568098
http://dx.doi.org/10.3389/fcimb.2021.739874