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SOCS3 Promotes ALV-J Virus Replication via Inhibiting JAK2/STAT3 Phosphorylation During Infection

Avian leukosis virus subgroup J (ALV-J) is an oncogenic retrovirus that causes immunosuppression and neoplastic diseases in poultry. Cytokine signal-transduction inhibitor molecule 3 (SOCS3) is an important negative regulator of the JAK2/STAT3 signaling pathway and plays certain roles in ALV-J infec...

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Detalles Bibliográficos
Autores principales: Mo, Guodong, Fu, Huali, Hu, Bowen, Zhang, Qihong, Xian, Mingjian, Zhang, Zihao, Lin, Ling, Shi, Meiqing, Nie, Qinghua, Zhang, Xiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461107/
https://www.ncbi.nlm.nih.gov/pubmed/34568100
http://dx.doi.org/10.3389/fcimb.2021.748795

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