Celecoxib Blocks Vasculogenic Mimicry via an Off-Target Effect to Radiosensitize Lung Cancer Cells: An Experimental Study

The resistance to radiotherapy in lung cancer can be attributed to vasculogenic mimicry (VM) to some extent. Celecoxib (CXB), a selective inhibitor of cyclooxygenase-2 (COX-2), is reported as a radiosensitizer in non-small cell lung cancer (NSCLC). However, whether CXB can regulate VM formation via...

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Detalles Bibliográficos
Autores principales: Niu, Kai, Chen, Xie-Wan, Qin, Yu, Zhang, Lu-Ping, Liao, Rong-Xia, Sun, Jian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461170/
https://www.ncbi.nlm.nih.gov/pubmed/34568026
http://dx.doi.org/10.3389/fonc.2021.697227

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