Cargando…

Comparing mortality from covid-19 to mortality due to overdose: A micromort analysis

OBJECTIVE: To compare the mortality risk due to covid-19 with death due to overdose in British Columbia, Canada. The opioid epidemic was declared a public health emergency in 2016. METHODS: Mortality risk was calculated in micromorts with covid-19 data for January–October 2020, derived from the BC c...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Yena, Lui, Leanna M.W., Brietzke, Elisa, Liao, Yuhua, Lu, Ciyong, Ho, Roger, Subramaniapillai, Mehala, Mansur, Rodrigo B., Rosenblat, Joshua D., McIntyre, Roger S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461265/
https://www.ncbi.nlm.nih.gov/pubmed/34656039
http://dx.doi.org/10.1016/j.jad.2021.09.059
_version_ 1784571940074160128
author Lee, Yena
Lui, Leanna M.W.
Brietzke, Elisa
Liao, Yuhua
Lu, Ciyong
Ho, Roger
Subramaniapillai, Mehala
Mansur, Rodrigo B.
Rosenblat, Joshua D.
McIntyre, Roger S.
author_facet Lee, Yena
Lui, Leanna M.W.
Brietzke, Elisa
Liao, Yuhua
Lu, Ciyong
Ho, Roger
Subramaniapillai, Mehala
Mansur, Rodrigo B.
Rosenblat, Joshua D.
McIntyre, Roger S.
author_sort Lee, Yena
collection PubMed
description OBJECTIVE: To compare the mortality risk due to covid-19 with death due to overdose in British Columbia, Canada. The opioid epidemic was declared a public health emergency in 2016. METHODS: Mortality risk was calculated in micromorts with covid-19 data for January–October 2020, derived from the BC center for Disease Control, and illicit drug toxicity deaths for January 2010–September 2020, derived from the BC Coroners Service. Age-stratified covid-19 incidence and deaths per 100,000 population and age-stratified illicit drug toxicity death rates per 100,000 population were calculated. A micromort is a unit of risk equivalent to a one-in-a-million chance of death. RESULTS: During the covid-19 pandemic, illicit drug toxicity deaths reached 1.0 micromorts per day, representing an increase of 0.5 micromorts per day relative to 2019 rates. In comparison, covid-19 mortality risk was 0.05 micromorts per day among individuals from the general population living in British Columbia and 21.1 micromorts per day among those infected with covid-19. Covid-related mortality risk was significantly lower among individuals aged <60 years, relative to older adults, whereas drug toxicity-related mortality was highest for individuals aged 30–59 years. CONCLUSIONS: The mortality associated with covid-19 is apparent and distributed unevenly across subpopulations. The mortality due to overdose has increased during covid-19 and exceeds mortality due to covid-19. Our results instantiate the triple threat caused by covid-19 (i.e., public health crisis, economic crisis and mental health crisis) and quantitatively highlight the externality of increased mortality due to deaths of despair in response to public health efforts to reduce covid-related mortality.
format Online
Article
Text
id pubmed-8461265
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-84612652021-09-24 Comparing mortality from covid-19 to mortality due to overdose: A micromort analysis Lee, Yena Lui, Leanna M.W. Brietzke, Elisa Liao, Yuhua Lu, Ciyong Ho, Roger Subramaniapillai, Mehala Mansur, Rodrigo B. Rosenblat, Joshua D. McIntyre, Roger S. J Affect Disord Research Paper OBJECTIVE: To compare the mortality risk due to covid-19 with death due to overdose in British Columbia, Canada. The opioid epidemic was declared a public health emergency in 2016. METHODS: Mortality risk was calculated in micromorts with covid-19 data for January–October 2020, derived from the BC center for Disease Control, and illicit drug toxicity deaths for January 2010–September 2020, derived from the BC Coroners Service. Age-stratified covid-19 incidence and deaths per 100,000 population and age-stratified illicit drug toxicity death rates per 100,000 population were calculated. A micromort is a unit of risk equivalent to a one-in-a-million chance of death. RESULTS: During the covid-19 pandemic, illicit drug toxicity deaths reached 1.0 micromorts per day, representing an increase of 0.5 micromorts per day relative to 2019 rates. In comparison, covid-19 mortality risk was 0.05 micromorts per day among individuals from the general population living in British Columbia and 21.1 micromorts per day among those infected with covid-19. Covid-related mortality risk was significantly lower among individuals aged <60 years, relative to older adults, whereas drug toxicity-related mortality was highest for individuals aged 30–59 years. CONCLUSIONS: The mortality associated with covid-19 is apparent and distributed unevenly across subpopulations. The mortality due to overdose has increased during covid-19 and exceeds mortality due to covid-19. Our results instantiate the triple threat caused by covid-19 (i.e., public health crisis, economic crisis and mental health crisis) and quantitatively highlight the externality of increased mortality due to deaths of despair in response to public health efforts to reduce covid-related mortality. Elsevier B.V. 2022-01-01 2021-09-24 /pmc/articles/PMC8461265/ /pubmed/34656039 http://dx.doi.org/10.1016/j.jad.2021.09.059 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Research Paper
Lee, Yena
Lui, Leanna M.W.
Brietzke, Elisa
Liao, Yuhua
Lu, Ciyong
Ho, Roger
Subramaniapillai, Mehala
Mansur, Rodrigo B.
Rosenblat, Joshua D.
McIntyre, Roger S.
Comparing mortality from covid-19 to mortality due to overdose: A micromort analysis
title Comparing mortality from covid-19 to mortality due to overdose: A micromort analysis
title_full Comparing mortality from covid-19 to mortality due to overdose: A micromort analysis
title_fullStr Comparing mortality from covid-19 to mortality due to overdose: A micromort analysis
title_full_unstemmed Comparing mortality from covid-19 to mortality due to overdose: A micromort analysis
title_short Comparing mortality from covid-19 to mortality due to overdose: A micromort analysis
title_sort comparing mortality from covid-19 to mortality due to overdose: a micromort analysis
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461265/
https://www.ncbi.nlm.nih.gov/pubmed/34656039
http://dx.doi.org/10.1016/j.jad.2021.09.059
work_keys_str_mv AT leeyena comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT luileannamw comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT brietzkeelisa comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT liaoyuhua comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT luciyong comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT horoger comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT subramaniapillaimehala comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT mansurrodrigob comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT rosenblatjoshuad comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis
AT mcintyrerogers comparingmortalityfromcovid19tomortalityduetooverdoseamicromortanalysis