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Characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre–Robin sequence

OBJECTIVE: To investigate the phenotypes and predominant skeletodental pattern in pre-adolescent patients with Pierre–Robin sequence (PRS). METHODS: The samples consisted of 26 Korean pre-adolescent PRS patients (11 boys and 15 girls; mean age at the investigation, 9.20 years) treated at the Departm...

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Autores principales: Yang, Il-Hyung, Chung, Jee Hyeok, Lee, Hyeok Joon, Cho, Il-Sik, Choi, Jin-Young, Lee, Jong-Ho, Kim, Sukwha, Baek, Seung-Hak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Orthodontists 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461384/
https://www.ncbi.nlm.nih.gov/pubmed/34556588
http://dx.doi.org/10.4041/kjod.2021.51.5.337
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author Yang, Il-Hyung
Chung, Jee Hyeok
Lee, Hyeok Joon
Cho, Il-Sik
Choi, Jin-Young
Lee, Jong-Ho
Kim, Sukwha
Baek, Seung-Hak
author_facet Yang, Il-Hyung
Chung, Jee Hyeok
Lee, Hyeok Joon
Cho, Il-Sik
Choi, Jin-Young
Lee, Jong-Ho
Kim, Sukwha
Baek, Seung-Hak
author_sort Yang, Il-Hyung
collection PubMed
description OBJECTIVE: To investigate the phenotypes and predominant skeletodental pattern in pre-adolescent patients with Pierre–Robin sequence (PRS). METHODS: The samples consisted of 26 Korean pre-adolescent PRS patients (11 boys and 15 girls; mean age at the investigation, 9.20 years) treated at the Department of Orthodontics, Seoul National University Dental Hospital between 1998 and 2019. Dental phenotypes, oral manifestation, cephalometric variables, and associated anomalies were investigated and statistically analyzed. RESULTS: Congenitally missing teeth (CMT) were found in 34.6% of the patients (n = 9/26, 20 teeth, 2.22 teeth per patient) with 55.5% (n = 5/9) exhibiting bilaterally symmetric missing pattern. The mandibular incisors were the most common CMT (n = 11/20). Predominant skeletodental patterns included Class II relationship (57.7%), posteriorly positioned maxilla (76.9%) and mandible (92.3%), hyper-divergent pattern (92.3%), high gonial angle (65.4%), small mandibular body length to anterior cranial base ratio (65.4%), linguoversion of the maxillary incisors (76.9%), and linguoversion of the mandibular incisors (80.8%). Incomplete cleft palate (CP) of hard palate with complete CP of soft palate (61.5%) was the most frequently observed, followed by complete CP of hard and soft palate (19.2%) and CP of soft palate (19.2%) (p < 0.05). However, CP severity did not show a significant correlation with any cephalometric variables except incisor mandibular plane angle (p < 0.05). Five craniofacial and 15 extra-craniofacial anomalies were observed (53.8% patients); this implicated the need of routine screening. CONCLUSIONS: The results might provide primary data for individualized diagnosis and treatment planning for pre-adolescent PRS patients despite a single institution-based data.
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spelling pubmed-84613842021-10-08 Characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre–Robin sequence Yang, Il-Hyung Chung, Jee Hyeok Lee, Hyeok Joon Cho, Il-Sik Choi, Jin-Young Lee, Jong-Ho Kim, Sukwha Baek, Seung-Hak Korean J Orthod Original Article OBJECTIVE: To investigate the phenotypes and predominant skeletodental pattern in pre-adolescent patients with Pierre–Robin sequence (PRS). METHODS: The samples consisted of 26 Korean pre-adolescent PRS patients (11 boys and 15 girls; mean age at the investigation, 9.20 years) treated at the Department of Orthodontics, Seoul National University Dental Hospital between 1998 and 2019. Dental phenotypes, oral manifestation, cephalometric variables, and associated anomalies were investigated and statistically analyzed. RESULTS: Congenitally missing teeth (CMT) were found in 34.6% of the patients (n = 9/26, 20 teeth, 2.22 teeth per patient) with 55.5% (n = 5/9) exhibiting bilaterally symmetric missing pattern. The mandibular incisors were the most common CMT (n = 11/20). Predominant skeletodental patterns included Class II relationship (57.7%), posteriorly positioned maxilla (76.9%) and mandible (92.3%), hyper-divergent pattern (92.3%), high gonial angle (65.4%), small mandibular body length to anterior cranial base ratio (65.4%), linguoversion of the maxillary incisors (76.9%), and linguoversion of the mandibular incisors (80.8%). Incomplete cleft palate (CP) of hard palate with complete CP of soft palate (61.5%) was the most frequently observed, followed by complete CP of hard and soft palate (19.2%) and CP of soft palate (19.2%) (p < 0.05). However, CP severity did not show a significant correlation with any cephalometric variables except incisor mandibular plane angle (p < 0.05). Five craniofacial and 15 extra-craniofacial anomalies were observed (53.8% patients); this implicated the need of routine screening. CONCLUSIONS: The results might provide primary data for individualized diagnosis and treatment planning for pre-adolescent PRS patients despite a single institution-based data. Korean Association of Orthodontists 2021-09-30 2021-09-30 /pmc/articles/PMC8461384/ /pubmed/34556588 http://dx.doi.org/10.4041/kjod.2021.51.5.337 Text en © 2021 The Korean Association of Orthodontists. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yang, Il-Hyung
Chung, Jee Hyeok
Lee, Hyeok Joon
Cho, Il-Sik
Choi, Jin-Young
Lee, Jong-Ho
Kim, Sukwha
Baek, Seung-Hak
Characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre–Robin sequence
title Characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre–Robin sequence
title_full Characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre–Robin sequence
title_fullStr Characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre–Robin sequence
title_full_unstemmed Characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre–Robin sequence
title_short Characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with Pierre–Robin sequence
title_sort characterization of phenotypes and predominant skeletodental patterns in pre-adolescent patients with pierre–robin sequence
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461384/
https://www.ncbi.nlm.nih.gov/pubmed/34556588
http://dx.doi.org/10.4041/kjod.2021.51.5.337
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