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The Unexplored Importance of Fleeting Chiral Intermediates in Enzyme-Catalyzed Reactions
[Image: see text] Decades of extensive research efforts by biochemists, organic chemists, and protein engineers have led to an understanding of the basic mechanisms of essentially all known types of enzymes, but in a formidable number of cases an essential aspect has been overlooked. The occurrence...
Autores principales: | Reetz, Manfred T., Garcia-Borràs, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461649/ https://www.ncbi.nlm.nih.gov/pubmed/34491742 http://dx.doi.org/10.1021/jacs.1c04551 |
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