Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term which describes patients who have developed a low platelet count and prothrombotic tendencies secondary to receiving a vaccine. The concept has been derived from the well-established phenomenon of heparin-induced th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461674/ https://www.ncbi.nlm.nih.gov/pubmed/34556531 http://dx.doi.org/10.1136/bcr-2021-245092 |
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author | Purkayastha, Pujon Mckechnie, Charlie Kalkur, Pallavi Scully, Marie |
author_facet | Purkayastha, Pujon Mckechnie, Charlie Kalkur, Pallavi Scully, Marie |
author_sort | Purkayastha, Pujon |
collection | PubMed |
description | Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term which describes patients who have developed a low platelet count and prothrombotic tendencies secondary to receiving a vaccine. The concept has been derived from the well-established phenomenon of heparin-induced thrombocytopenia, and several cases of VITT have now been reported in patients who have received the AstraZeneca (ChAdOx1 nCov-19) vaccine. Unfortunately, some of these patients have gone on to develop intracranial venous sinus thrombosis. We present a case of VITT-associated sinus thrombosis secondary to the AstraZeneca (ChAdOx1 nCov-19) vaccine, which was complicated by a large intracerebral haemorrhage. |
format | Online Article Text |
id | pubmed-8461674 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-84616742021-10-08 Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis Purkayastha, Pujon Mckechnie, Charlie Kalkur, Pallavi Scully, Marie BMJ Case Rep Case Report Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term which describes patients who have developed a low platelet count and prothrombotic tendencies secondary to receiving a vaccine. The concept has been derived from the well-established phenomenon of heparin-induced thrombocytopenia, and several cases of VITT have now been reported in patients who have received the AstraZeneca (ChAdOx1 nCov-19) vaccine. Unfortunately, some of these patients have gone on to develop intracranial venous sinus thrombosis. We present a case of VITT-associated sinus thrombosis secondary to the AstraZeneca (ChAdOx1 nCov-19) vaccine, which was complicated by a large intracerebral haemorrhage. BMJ Publishing Group 2021-09-23 /pmc/articles/PMC8461674/ /pubmed/34556531 http://dx.doi.org/10.1136/bcr-2021-245092 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. |
spellingShingle | Case Report Purkayastha, Pujon Mckechnie, Charlie Kalkur, Pallavi Scully, Marie Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis |
title | Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis |
title_full | Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis |
title_fullStr | Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis |
title_full_unstemmed | Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis |
title_short | Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis |
title_sort | rare case of covid-19 vaccine-associated intracranial haemorrhage with venous sinus thrombosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461674/ https://www.ncbi.nlm.nih.gov/pubmed/34556531 http://dx.doi.org/10.1136/bcr-2021-245092 |
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