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Nasal Immunization With Small Molecule Mast Cell Activators Enhance Immunity to Co-Administered Subunit Immunogens

Mast cell activators are a novel class of mucosal vaccine adjuvants. The polymeric compound, Compound 48/80 (C48/80), and cationic peptide, Mastoparan 7 (M7) are mast cell activators that provide adjuvant activity when administered by the nasal route. However, small molecule mast cell activators may...

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Detalles Bibliográficos
Autores principales:	Johnson-Weaver, Brandi T., Choi, Hae Woong, Yang, Hang, Granek, Josh A., Chan, Cliburn, Abraham, Soman N., Staats, Herman F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461742/ https://www.ncbi.nlm.nih.gov/pubmed/34566991 http://dx.doi.org/10.3389/fimmu.2021.730346

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