Histone-mutant glioma presenting as diffuse leptomeningeal disease

Glioblastoma multiforme is the most common malignant primary brain tumor in adults. Histone H3 mutations have been identified in pediatric and adult gliomas, with H3K27M mutations typically associated with a posterior fossa midline tumor location and poor prognosis. Leptomeningeal disease is a known...

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Detalles Bibliográficos
Autores principales: Nadkarni, Tanvi, Hamilton, Kimberly, Niazi, Faraze, Ward, Melanie, Okakpu, Uchenna, Castellani, Rudolph J, Prisneac, Ion, Sener, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461753/
https://www.ncbi.nlm.nih.gov/pubmed/34469205
http://dx.doi.org/10.2217/cns-2021-0008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461753/
https://www.ncbi.nlm.nih.gov/pubmed/34469205
http://dx.doi.org/10.2217/cns-2021-0008

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