CMTM3 suppresses chordoma progress through EGFR/STAT3 regulated EMT and TP53 signaling pathway

BACKGROUND: Chordomas are rare, slow-growing and locally aggressive bone sarcomas. At present, chordomas are difficult to manage due to their high recurrence rate, metastasis tendency and poor prognosis. The underlying mechanisms of chordoma tumorigenesis and progression urgently need to be explored...

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Detalles Bibliográficos
Autores principales: Yuan, Wanqiong, Wei, Feng, Ouyang, Hanqiang, Ren, Xiaoqing, Hang, Jing, Mo, Xiaoning, Liu, Zhongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461898/
https://www.ncbi.nlm.nih.gov/pubmed/34560882
http://dx.doi.org/10.1186/s12935-021-02159-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461898/
https://www.ncbi.nlm.nih.gov/pubmed/34560882
http://dx.doi.org/10.1186/s12935-021-02159-5

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