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Rolipram plays an anti-fibrotic effect in ligamentum flavum fibroblasts by inhibiting the activation of ERK1/2

BACKGROUND: Fibrosis is an important factor and process of ligamentum flavum hypertrophy. The expression of phosphodiesterase family (PDE) is related to inflammation and fibrosis. This article studied the expression of PDE in hypertrophic ligamentum flavum fibroblasts and investigated whether inhibi...

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Detalles Bibliográficos
Autores principales:	Wu, Likang, Xu, Lei, Chen, Yu, Xu, Guohua, Guo, Qunfeng, Meng, Depeng, Fan, Jianping, Song, Guoqiang, Xu, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8461931/ https://www.ncbi.nlm.nih.gov/pubmed/34556093 http://dx.doi.org/10.1186/s12891-021-04712-9

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