mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021

Through deterministic data linkage of health registries, mRNA vaccine effectiveness (VE) against COVID-19-related hospitalisations and deaths was measured in 1,880,351 older adults. VE against hospitalisations was 94% (95% confidence interval (CI): 88–97) and 82% (95% CI: 72–89) for those 65–79 and...

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Detalles Bibliográficos
Autores principales: Nunes, Baltazar, Rodrigues, Ana Paula, Kislaya, Irina, Cruz, Camila, Peralta-Santos, André, Lima, João, Pinto Leite, Pedro, Sequeira, Duarte, Matias Dias, Carlos, Machado, Ausenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462036/
https://www.ncbi.nlm.nih.gov/pubmed/34558406
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.38.2100833
Descripción
Sumario:Through deterministic data linkage of health registries, mRNA vaccine effectiveness (VE) against COVID-19-related hospitalisations and deaths was measured in 1,880,351 older adults. VE against hospitalisations was 94% (95% confidence interval (CI): 88–97) and 82% (95% CI: 72–89) for those 65–79 and ≥ 80 years old, with no evidence of waning 98 days after dose two. VE against mortality was 96% (95% CI: 92–98) and 81% (95% CI: 74–87) in these two age groups.

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