mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021

Through deterministic data linkage of health registries, mRNA vaccine effectiveness (VE) against COVID-19-related hospitalisations and deaths was measured in 1,880,351 older adults. VE against hospitalisations was 94% (95% confidence interval (CI): 88–97) and 82% (95% CI: 72–89) for those 65–79 and...

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Autores principales: Nunes, Baltazar, Rodrigues, Ana Paula, Kislaya, Irina, Cruz, Camila, Peralta-Santos, André, Lima, João, Pinto Leite, Pedro, Sequeira, Duarte, Matias Dias, Carlos, Machado, Ausenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462036/
https://www.ncbi.nlm.nih.gov/pubmed/34558406
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.38.2100833
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author Nunes, Baltazar
Rodrigues, Ana Paula
Kislaya, Irina
Cruz, Camila
Peralta-Santos, André
Lima, João
Pinto Leite, Pedro
Sequeira, Duarte
Matias Dias, Carlos
Machado, Ausenda
author_facet Nunes, Baltazar
Rodrigues, Ana Paula
Kislaya, Irina
Cruz, Camila
Peralta-Santos, André
Lima, João
Pinto Leite, Pedro
Sequeira, Duarte
Matias Dias, Carlos
Machado, Ausenda
author_sort Nunes, Baltazar
collection PubMed
description Through deterministic data linkage of health registries, mRNA vaccine effectiveness (VE) against COVID-19-related hospitalisations and deaths was measured in 1,880,351 older adults. VE against hospitalisations was 94% (95% confidence interval (CI): 88–97) and 82% (95% CI: 72–89) for those 65–79 and ≥ 80 years old, with no evidence of waning 98 days after dose two. VE against mortality was 96% (95% CI: 92–98) and 81% (95% CI: 74–87) in these two age groups.
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spelling pubmed-84620362021-10-18 mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021 Nunes, Baltazar Rodrigues, Ana Paula Kislaya, Irina Cruz, Camila Peralta-Santos, André Lima, João Pinto Leite, Pedro Sequeira, Duarte Matias Dias, Carlos Machado, Ausenda Euro Surveill Rapid Communication Through deterministic data linkage of health registries, mRNA vaccine effectiveness (VE) against COVID-19-related hospitalisations and deaths was measured in 1,880,351 older adults. VE against hospitalisations was 94% (95% confidence interval (CI): 88–97) and 82% (95% CI: 72–89) for those 65–79 and ≥ 80 years old, with no evidence of waning 98 days after dose two. VE against mortality was 96% (95% CI: 92–98) and 81% (95% CI: 74–87) in these two age groups. European Centre for Disease Prevention and Control (ECDC) 2021-09-23 /pmc/articles/PMC8462036/ /pubmed/34558406 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.38.2100833 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Nunes, Baltazar
Rodrigues, Ana Paula
Kislaya, Irina
Cruz, Camila
Peralta-Santos, André
Lima, João
Pinto Leite, Pedro
Sequeira, Duarte
Matias Dias, Carlos
Machado, Ausenda
mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021
title mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021
title_full mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021
title_fullStr mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021
title_full_unstemmed mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021
title_short mRNA vaccine effectiveness against COVID-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in Portugal, February to August 2021
title_sort mrna vaccine effectiveness against covid-19-related hospitalisations and deaths in older adults: a cohort study based on data linkage of national health registries in portugal, february to august 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462036/
https://www.ncbi.nlm.nih.gov/pubmed/34558406
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.38.2100833
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