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Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor?

BACKGROUND: The aim of this study was to evaluate the donor criteria used in lung transplantation in our clinic. METHODS: A total of 55 cadaveric donors who were accepted for lung transplantation in our clinic between December 2016 and January 2019 were retrospectively analyzed according to ideal do...

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Autores principales: Vayvada, Mustafa, Taşçı, Ahmet Erdal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bayçınar Medical Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462116/
https://www.ncbi.nlm.nih.gov/pubmed/34589252
http://dx.doi.org/10.5606/tgkdc.dergisi.2021.19953
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author Vayvada, Mustafa
Taşçı, Ahmet Erdal
author_facet Vayvada, Mustafa
Taşçı, Ahmet Erdal
author_sort Vayvada, Mustafa
collection PubMed
description BACKGROUND: The aim of this study was to evaluate the donor criteria used in lung transplantation in our clinic. METHODS: A total of 55 cadaveric donors who were accepted for lung transplantation in our clinic between December 2016 and January 2019 were retrospectively analyzed according to ideal donor criteria. The donors were divided into two groups as ideal and non-ideal ones according to their age, partial pressure of oxygen in arterial blood, history of smoking, and ventilation day. Donor data, recipient characteristics and survival outcomes were evaluated. RESULTS: Of 55 donors accepted for lung transplantation, 24 (43.7%) were ideal and 31 (56.3%) were non-ideal donors. The 90-day mortality and one-year survival rates were not significantly different between the two groups. The 90-day mortality was 25% in the ideal group and 22.6% in the non-ideal group (p=0.834). The one-year survival rates after lung transplantation were 64.5% versus 70.6% in the ideal and non-ideal groups, respectively (p=0.444). CONCLUSION: The whole clinical picture should be evaluated before accepting or rejecting donors for lung transplantation. The use of lung donors that do not meet the ideal criteria does not impair short- and mid-term results, compared to ideal lung donors. Strict implementation of donor criteria may prevent using suitable donors for lung transplantation. Use of non-ideal donors can reduce waiting list mortality.
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spelling pubmed-84621162021-09-28 Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor? Vayvada, Mustafa Taşçı, Ahmet Erdal Turk Gogus Kalp Damar Cerrahisi Derg Original Article BACKGROUND: The aim of this study was to evaluate the donor criteria used in lung transplantation in our clinic. METHODS: A total of 55 cadaveric donors who were accepted for lung transplantation in our clinic between December 2016 and January 2019 were retrospectively analyzed according to ideal donor criteria. The donors were divided into two groups as ideal and non-ideal ones according to their age, partial pressure of oxygen in arterial blood, history of smoking, and ventilation day. Donor data, recipient characteristics and survival outcomes were evaluated. RESULTS: Of 55 donors accepted for lung transplantation, 24 (43.7%) were ideal and 31 (56.3%) were non-ideal donors. The 90-day mortality and one-year survival rates were not significantly different between the two groups. The 90-day mortality was 25% in the ideal group and 22.6% in the non-ideal group (p=0.834). The one-year survival rates after lung transplantation were 64.5% versus 70.6% in the ideal and non-ideal groups, respectively (p=0.444). CONCLUSION: The whole clinical picture should be evaluated before accepting or rejecting donors for lung transplantation. The use of lung donors that do not meet the ideal criteria does not impair short- and mid-term results, compared to ideal lung donors. Strict implementation of donor criteria may prevent using suitable donors for lung transplantation. Use of non-ideal donors can reduce waiting list mortality. Bayçınar Medical Publishing 2021-07-26 /pmc/articles/PMC8462116/ /pubmed/34589252 http://dx.doi.org/10.5606/tgkdc.dergisi.2021.19953 Text en Copyright © 2021, Turkish Society of Cardiovascular Surgery https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Article
Vayvada, Mustafa
Taşçı, Ahmet Erdal
Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor?
title Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor?
title_full Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor?
title_fullStr Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor?
title_full_unstemmed Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor?
title_short Donor selection for lung transplant in Turkey: Is it necessary to wait for an ideal donor?
title_sort donor selection for lung transplant in turkey: is it necessary to wait for an ideal donor?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462116/
https://www.ncbi.nlm.nih.gov/pubmed/34589252
http://dx.doi.org/10.5606/tgkdc.dergisi.2021.19953
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