Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer

Emerging studies have showed irreversible electroporation (IRE) focused on pancreatic cancer (PC). However, the effects of IRE treatment on the immune response of PC remain unknown. Moreover, there are few studies on the therapeutic effect of IRE combining with immunotherapy on PC. Thus, we review r...

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Autores principales: Tian, Guo, Guan, Jiajia, Chu, Yanhua, Zhao, Qiyu, Jiang, Tian’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462269/
https://www.ncbi.nlm.nih.gov/pubmed/34568040
http://dx.doi.org/10.3389/fonc.2021.712042
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author Tian, Guo
Guan, Jiajia
Chu, Yanhua
Zhao, Qiyu
Jiang, Tian’an
author_facet Tian, Guo
Guan, Jiajia
Chu, Yanhua
Zhao, Qiyu
Jiang, Tian’an
author_sort Tian, Guo
collection PubMed
description Emerging studies have showed irreversible electroporation (IRE) focused on pancreatic cancer (PC). However, the effects of IRE treatment on the immune response of PC remain unknown. Moreover, there are few studies on the therapeutic effect of IRE combining with immunotherapy on PC. Thus, we review recent advances in our understanding of IRE alone and its working with immunotherapy towards the immune response of PC, discussing potential opportunities for exploring future treatment strategies.
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spelling pubmed-84622692021-09-25 Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer Tian, Guo Guan, Jiajia Chu, Yanhua Zhao, Qiyu Jiang, Tian’an Front Oncol Oncology Emerging studies have showed irreversible electroporation (IRE) focused on pancreatic cancer (PC). However, the effects of IRE treatment on the immune response of PC remain unknown. Moreover, there are few studies on the therapeutic effect of IRE combining with immunotherapy on PC. Thus, we review recent advances in our understanding of IRE alone and its working with immunotherapy towards the immune response of PC, discussing potential opportunities for exploring future treatment strategies. Frontiers Media S.A. 2021-09-10 /pmc/articles/PMC8462269/ /pubmed/34568040 http://dx.doi.org/10.3389/fonc.2021.712042 Text en Copyright © 2021 Tian, Guan, Chu, Zhao and Jiang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Tian, Guo
Guan, Jiajia
Chu, Yanhua
Zhao, Qiyu
Jiang, Tian’an
Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer
title Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer
title_full Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer
title_fullStr Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer
title_full_unstemmed Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer
title_short Immunomodulatory Effect of Irreversible Electroporation Alone and Its Cooperating With Immunotherapy in Pancreatic Cancer
title_sort immunomodulatory effect of irreversible electroporation alone and its cooperating with immunotherapy in pancreatic cancer
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462269/
https://www.ncbi.nlm.nih.gov/pubmed/34568040
http://dx.doi.org/10.3389/fonc.2021.712042
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