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The Role of Akt in Acquired Cetuximab Resistant Head and Neck Squamous Cell Carcinoma: An In Vitro Study on a Novel Combination Strategy

The epidermal growth factor receptor (EGFR) is a therapeutic target in head and neck squamous cell carcinoma (HNSCC). Resistance to EGFR-targeted therapies, such as cetuximab, poses a challenging problem. This study aims to characterize acquired cetuximab resistance mechanisms in HNSCC cell lines by...

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Detalles Bibliográficos
Autores principales:	Zaryouh, Hannah, De Pauw, Ines, Baysal, Hasan, Pauwels, Patrick, Peeters, Marc, Vermorken, Jan Baptist, Lardon, Filip, Wouters, An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462273/ https://www.ncbi.nlm.nih.gov/pubmed/34568028 http://dx.doi.org/10.3389/fonc.2021.697967

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