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Stromal Galectin-1 Promotes Colorectal Cancer Cancer-Initiating Cell Features and Disease Dissemination Through SOX9 and β-Catenin: Development of Niche-Based Biomarkers

Over 90% of colorectal cancer (CRC) patients have mutations in the Wnt/β-catenin pathway, making the development of biomarkers difficult based on this critical oncogenic pathway. Recent studies demonstrate that CRC tumor niche-stromal cells can activate β-catenin in cancer-initiating cells (CICs), l...

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Detalles Bibliográficos
Autores principales:	Peng, Kai-Yen, Jiang, Shih-Sheng, Lee, Yu-Wei, Tsai, Fang-Yu, Chang, Chia-Chi, Chen, Li-Tzong, Yen, B. Linju
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462299/ https://www.ncbi.nlm.nih.gov/pubmed/34568045 http://dx.doi.org/10.3389/fonc.2021.716055

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