SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA

We report persistent severe acute respiratory syndrome coronavirus 2 infection in a patient with HIV/AIDS; the virus developed spike N terminal domain and receptor binding domain neutralization resistance mutations. Our findings suggest that immunocompromised patients can harbor emerging variants of...

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Autores principales: Hoffman, Seth A., Costales, Cristina, Sahoo, Malaya K., Palanisamy, Srikanth, Yamamoto, Fumiko, Huang, ChunHong, Verghese, Michelle, Solis, Daniel A., Sibai, Mamdouh, Subramanian, Aruna, Tompkins, Lucy S., Grant, Philip, Shafer, Robert W., Pinsky, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462335/
https://www.ncbi.nlm.nih.gov/pubmed/34296992
http://dx.doi.org/10.3201/eid2710.211461
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author Hoffman, Seth A.
Costales, Cristina
Sahoo, Malaya K.
Palanisamy, Srikanth
Yamamoto, Fumiko
Huang, ChunHong
Verghese, Michelle
Solis, Daniel A.
Sibai, Mamdouh
Subramanian, Aruna
Tompkins, Lucy S.
Grant, Philip
Shafer, Robert W.
Pinsky, Benjamin A.
author_facet Hoffman, Seth A.
Costales, Cristina
Sahoo, Malaya K.
Palanisamy, Srikanth
Yamamoto, Fumiko
Huang, ChunHong
Verghese, Michelle
Solis, Daniel A.
Sibai, Mamdouh
Subramanian, Aruna
Tompkins, Lucy S.
Grant, Philip
Shafer, Robert W.
Pinsky, Benjamin A.
author_sort Hoffman, Seth A.
collection PubMed
description We report persistent severe acute respiratory syndrome coronavirus 2 infection in a patient with HIV/AIDS; the virus developed spike N terminal domain and receptor binding domain neutralization resistance mutations. Our findings suggest that immunocompromised patients can harbor emerging variants of severe acute respiratory syndrome coronavirus 2.
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spelling pubmed-84623352021-10-07 SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA Hoffman, Seth A. Costales, Cristina Sahoo, Malaya K. Palanisamy, Srikanth Yamamoto, Fumiko Huang, ChunHong Verghese, Michelle Solis, Daniel A. Sibai, Mamdouh Subramanian, Aruna Tompkins, Lucy S. Grant, Philip Shafer, Robert W. Pinsky, Benjamin A. Emerg Infect Dis Research Letter We report persistent severe acute respiratory syndrome coronavirus 2 infection in a patient with HIV/AIDS; the virus developed spike N terminal domain and receptor binding domain neutralization resistance mutations. Our findings suggest that immunocompromised patients can harbor emerging variants of severe acute respiratory syndrome coronavirus 2. Centers for Disease Control and Prevention 2021-10 /pmc/articles/PMC8462335/ /pubmed/34296992 http://dx.doi.org/10.3201/eid2710.211461 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Hoffman, Seth A.
Costales, Cristina
Sahoo, Malaya K.
Palanisamy, Srikanth
Yamamoto, Fumiko
Huang, ChunHong
Verghese, Michelle
Solis, Daniel A.
Sibai, Mamdouh
Subramanian, Aruna
Tompkins, Lucy S.
Grant, Philip
Shafer, Robert W.
Pinsky, Benjamin A.
SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA
title SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA
title_full SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA
title_fullStr SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA
title_full_unstemmed SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA
title_short SARS-CoV-2 Neutralization Resistance Mutations in Patient with HIV/AIDS, California, USA
title_sort sars-cov-2 neutralization resistance mutations in patient with hiv/aids, california, usa
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462335/
https://www.ncbi.nlm.nih.gov/pubmed/34296992
http://dx.doi.org/10.3201/eid2710.211461
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