Vacuolization of hematopoietic precursors: an enigma with multiple etiologies

Cytoplasmic vacuoles in precursors can be seen in a number of clinical settings, including copper deficiency, zinc toxicity, alcohol abuse, antibiotic treatment, myelodysplasia, and VEXAS syndrome. Gurnari et al asked how common VEXAS syndrome is in patients whose bone marrow aspirates show this dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Gurnari, Carmelo, Pagliuca, Simona, Durkin, Lisa, Terkawi, Laila, Awada, Hassan, Kongkiatkamon, Sunisa, Zawit, Misam, Hsi, Eric D., Carraway, Hetty E., Rogers, Heesun J., Visconte, Valeria, Maciejewski, Jaroslaw P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Letter to Blood
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462399/
https://www.ncbi.nlm.nih.gov/pubmed/33690844
http://dx.doi.org/10.1182/blood.2021010811
Descripción
Sumario:Cytoplasmic vacuoles in precursors can be seen in a number of clinical settings, including copper deficiency, zinc toxicity, alcohol abuse, antibiotic treatment, myelodysplasia, and VEXAS syndrome. Gurnari et al asked how common VEXAS syndrome is in patients whose bone marrow aspirates show this distinctive feature, finding 2 diagnoses of VEXAS among 24 cases with vacuoles.

Ejemplares similares