Vacuolization of hematopoietic precursors: an enigma with multiple etiologies

Cytoplasmic vacuoles in precursors can be seen in a number of clinical settings, including copper deficiency, zinc toxicity, alcohol abuse, antibiotic treatment, myelodysplasia, and VEXAS syndrome. Gurnari et al asked how common VEXAS syndrome is in patients whose bone marrow aspirates show this dis...

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Autores principales: Gurnari, Carmelo, Pagliuca, Simona, Durkin, Lisa, Terkawi, Laila, Awada, Hassan, Kongkiatkamon, Sunisa, Zawit, Misam, Hsi, Eric D., Carraway, Hetty E., Rogers, Heesun J., Visconte, Valeria, Maciejewski, Jaroslaw P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Letter to Blood
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462399/
https://www.ncbi.nlm.nih.gov/pubmed/33690844
http://dx.doi.org/10.1182/blood.2021010811
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author Gurnari, Carmelo
Pagliuca, Simona
Durkin, Lisa
Terkawi, Laila
Awada, Hassan
Kongkiatkamon, Sunisa
Zawit, Misam
Hsi, Eric D.
Carraway, Hetty E.
Rogers, Heesun J.
Visconte, Valeria
Maciejewski, Jaroslaw P.
author_facet Gurnari, Carmelo
Pagliuca, Simona
Durkin, Lisa
Terkawi, Laila
Awada, Hassan
Kongkiatkamon, Sunisa
Zawit, Misam
Hsi, Eric D.
Carraway, Hetty E.
Rogers, Heesun J.
Visconte, Valeria
Maciejewski, Jaroslaw P.
author_sort Gurnari, Carmelo
collection PubMed
description Cytoplasmic vacuoles in precursors can be seen in a number of clinical settings, including copper deficiency, zinc toxicity, alcohol abuse, antibiotic treatment, myelodysplasia, and VEXAS syndrome. Gurnari et al asked how common VEXAS syndrome is in patients whose bone marrow aspirates show this distinctive feature, finding 2 diagnoses of VEXAS among 24 cases with vacuoles.
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spelling pubmed-84623992022-07-01 Vacuolization of hematopoietic precursors: an enigma with multiple etiologies Gurnari, Carmelo Pagliuca, Simona Durkin, Lisa Terkawi, Laila Awada, Hassan Kongkiatkamon, Sunisa Zawit, Misam Hsi, Eric D. Carraway, Hetty E. Rogers, Heesun J. Visconte, Valeria Maciejewski, Jaroslaw P. Blood Letter to Blood Cytoplasmic vacuoles in precursors can be seen in a number of clinical settings, including copper deficiency, zinc toxicity, alcohol abuse, antibiotic treatment, myelodysplasia, and VEXAS syndrome. Gurnari et al asked how common VEXAS syndrome is in patients whose bone marrow aspirates show this distinctive feature, finding 2 diagnoses of VEXAS among 24 cases with vacuoles. American Society of Hematology 2021-07-01 /pmc/articles/PMC8462399/ /pubmed/33690844 http://dx.doi.org/10.1182/blood.2021010811 Text en © 2021 by The American Society of Hematology This article is made available via the PMC Open Access Subset for unrestricted reuse and analyses in any form or by any means with acknowledgment of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle Letter to Blood
Gurnari, Carmelo
Pagliuca, Simona
Durkin, Lisa
Terkawi, Laila
Awada, Hassan
Kongkiatkamon, Sunisa
Zawit, Misam
Hsi, Eric D.
Carraway, Hetty E.
Rogers, Heesun J.
Visconte, Valeria
Maciejewski, Jaroslaw P.
Vacuolization of hematopoietic precursors: an enigma with multiple etiologies
title Vacuolization of hematopoietic precursors: an enigma with multiple etiologies
title_full Vacuolization of hematopoietic precursors: an enigma with multiple etiologies
title_fullStr Vacuolization of hematopoietic precursors: an enigma with multiple etiologies
title_full_unstemmed Vacuolization of hematopoietic precursors: an enigma with multiple etiologies
title_short Vacuolization of hematopoietic precursors: an enigma with multiple etiologies
title_sort vacuolization of hematopoietic precursors: an enigma with multiple etiologies
topic Letter to Blood
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462399/
https://www.ncbi.nlm.nih.gov/pubmed/33690844
http://dx.doi.org/10.1182/blood.2021010811
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