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MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival

Cullin-4 ubiquitin ligase (CRL4) complexes are differentially composed and highly dynamic protein assemblies that control many biological processes, including the global genome nucleotide excision repair (GG-NER) pathway. Here, we identified the kinase mitogen-activated protein kinase kinase kinase...

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Detalles Bibliográficos
Autores principales:	Bacher, Susanne, Stekman, Hilda, Farah, Carla M., Karger, Annika, Kracht, Michael, Schmitz, M. Lienhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462458/ https://www.ncbi.nlm.nih.gov/pubmed/34251884 http://dx.doi.org/10.1128/MCB.00081-21

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