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Orai channel C-terminal peptides are key modulators of STlM-Orai coupling and calcium signal generation

Junctional coupling between endoplasmic reticulum (ER) Ca(2+)-sensor STIM proteins and plasma membrane (PM) Orai channels mediates Ca(2+) signals in most cells. We reveal that PM-tethered, fluorescently tagged C-terminal M4x (fourth transmembrane helix contains a cytoplasmic C-terminal extension) pe...

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Detalles Bibliográficos
Autores principales:	Baraniak, James H., Zhou, Yandong, Nwokonko, Robert M., Jennette, Michelle R., Kazzaz, Sarah A., Stenson, Jazmin M., Whitsell, Abigale L., Wang, Youjun, Trebak, Mohamed, Gill, Donald L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462482/ https://www.ncbi.nlm.nih.gov/pubmed/34192542 http://dx.doi.org/10.1016/j.celrep.2021.109322

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