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Oridonin Prolongs the Survival of Mouse Cardiac Allografts by Attenuating the NF-κB/NLRP3 Pathway

BACKGROUND: Oridonin (Ori), the main bioactive ingredient of the natural anti-inflammatory herb Rabdosia rubescens, could be a covalent inhibitor of the NLRP3 inflammasome. Solid organ transplantation provides a life-saving optional therapy for patients with end-stage organ dysfunction. The long-ter...

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Detalles Bibliográficos
Autores principales:	Du, Xiaoxiao, Que, Weitao, Hu, Xin, Yu, Xiao, Guo, Wen-Zhi, Zhang, Shuijun, Li, Xiao-Kang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462485/ https://www.ncbi.nlm.nih.gov/pubmed/34566976 http://dx.doi.org/10.3389/fimmu.2021.719574

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