Cargando…
Development of a novel ALK rearrangement screening test for non–small cell lung cancers
Approximately 5–7% of non–small cell lung cancer (NSCLC) cases harbor an anaplastic lymphoma kinase (ALK) fusion gene and may benefit from ALK inhibitor therapy. To detect ALK fusion genes, we developed a novel test using reverse transcription polymerase chain reaction (RT-PCR) for the ALK kinase do...
Autores principales: | Chen, Yi-Lin, Chen, Wan-Li, Cheng, Yi-Chia, Lin, Ming-Ching, Yang, Shu-Ching, Tsai, Hung-Wen, Lin, Chien‐Chung, Su, Wu-Chou, Chow, Nan-Haw, Ho, Chung-Liang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462717/ https://www.ncbi.nlm.nih.gov/pubmed/34559836 http://dx.doi.org/10.1371/journal.pone.0257152 |
Ejemplares similares
-
Five Technologies for Detecting the EGFR T790M Mutation in the Circulating Cell-Free DNA of Patients With Non-small Cell Lung Cancer: A Comparison
por: Chen, Yi-Lin, et al.
Publicado: (2019) -
Clinical implications of PNA‑sequencing as a complementary test for EGFR mutation analysis in human lung cancer
por: Chen, Yi-Lin, et al.
Publicado: (2023) -
High concordance rate of capillary electrophoresis workflow for microsatellite instability analysis and mismatch repair (MMR) immunostaining in colorectal carcinoma
por: Huang, Wenya, et al.
Publicado: (2023) -
The Impact of Clinical Factors, ALK Fusion Variants, and BIM Polymorphism on Crizotinib-Treated Advanced EML4–ALK Rearranged Non-small Cell Lung Cancer
por: Lin, Yen-Ting, et al.
Publicado: (2019) -
Epidermal Growth Factor Receptor Mutation and Anaplastic Lymphoma Kinase Gene Fusion: Detection in Malignant Pleural Effusion by RNA or PNA Analysis
por: Chen, Yi-Lin, et al.
Publicado: (2016)