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The chromatin remodeler Chd1 supports MRX and Exo1 functions in resection of DNA double-strand breaks

Repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) requires that the 5’-terminated DNA strands are resected to generate single-stranded DNA overhangs. This process is initiated by a short-range resection catalyzed by the MRX (Mre11-Rad50-Xrs2) complex, which is followed by a...

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Detalles Bibliográficos
Autores principales:	Gnugnoli, Marco, Casari, Erika, Longhese, Maria Pia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8462745/ https://www.ncbi.nlm.nih.gov/pubmed/34520455 http://dx.doi.org/10.1371/journal.pgen.1009807

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